Understanding Clinical Trials: Why Are They Important for Drug Development?

Read time: 3 minutes. This is Part 1 in a 3-part series explaining how new drugs and treatments get approved to treat lung cancer. Parts 2 and 3 will be published in the coming weeks. Have you ever wondered how a new medicine or drug to treat lung cancer is brought to the people who need it? That’s what clinical trials help us do. According to the National Cancer Institute, a clinical trial is a type of research study that tests how well new medical approaches (such as screening tests, prevention habits, or disease treatments) work in people. Sometimes, a clinical trial is called a clinical

Countdown to ILCSC24: Bringing the World’s Experts Right to Your Living Room

Read time: 3 minutes. One of LUNGevity’s two flagship survivorship events, the International Lung Cancer Survivorship Conference (ILCSC), is being held virtually September 20 – 21, 2024. This is a free, online event that allows people with lung cancer and caregivers from around the world to join from the comfort of their own homes and hear from a star-studded lineup of lung cancer experts discussing the latest advances in research and treatment. You can register today for free, or view the conference agenda. Last year’s conference was one of our most successful events yet, with over 900

How Can Patients and Researchers Design Clinical Trials Together?

Read time: 2 minutes. Traditionally, people associate getting involved in lung cancer research with enrolling in a clinical trial. But most don’t realize they can also partner with researchers behind the scenes and get involved in designing clinical trials. In the first of a three-part series, Rising Tide Foundation for Clinical Cancer Research has partnered with LUNGevity to understand the role people with lung cancer can play in developing clinical trials. Through panelist presentations and discussions, this video focuses on patient-centric endpoints, showcases this collaboration from the

2024 ASCO: Highlights of Lung Cancer Research

Read time: 8 minutes Thousands of oncologists, scientists, biotech and pharmaceutical representatives, patients, and advocates (including LUNGevity staff) met to discuss lifesaving cancer research at the  annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago from May 31 through June 4, 2024. The theme for this year’s conference, “The Art and Science of Cancer Care: From Comfort to Cure,” highlighted the importance of using both our creativity and our scientific prowess to increase access to treatment.   It’s a time when we’ve made and continue to make extraordinary

Is Lung Cancer in Young Adults Hereditary?

Read time: 2 minutes The question of whether lung cancer is hereditary is becoming increasingly important in the lung cancer community. While the average age of lung cancer diagnosis is approximately 70 years old, we are now seeing young adults in their 20s and 30s getting lung cancer. We currently suspect lung cancer in young adults may be caused by environmental factors (such as air pollution or chemical exposure), their genetic make-up, or some combination of these factors. We cannot say for certain if lung cancer is hereditary, but researchers are working to understand the causes of lung

Researcher Aims to Bring 360-Degree Care to Young Adults Living with Lung Cancer

Young adults (less than 50 years of age) are being diagnosed with lung cancer at increasing rates. They tend to be women of Hispanic or Asian descent and are typically diagnosed with advanced-stage lung cancer. Research is ongoing to help us develop effective options to treat these patients medically, but little is known about the effects of the diagnosis on their mental, social, and financial health or their family planning. To help us better understand the needs of this growing population, LUNGevity awarded one of its 2022 Health Equity and Inclusiveness Junior Investigator Awards to Narjust

Highlights of AACR 2024: Where the Laboratory Meets the Patient

Read time: 7 minutes It’s spring! The daffodils bloom, the days become longer, and I attend the annual meeting of the American Association for Cancer Research (AACR). For those of you who are new to this meeting, it is the largest gathering of laboratory scientists and clinicians in the world—coming together to discuss how to take science from the bench (laboratory) to patients and communities. This year’s meeting was held in sunny San Diego and brought together more than 23,000 attendees. Below I summarize key meeting highlights that are of interest to the lung cancer community. Lung Cancer

Cancer Grand Challenges Summit 2024: No Time to Waste in Addressing Some of Toughest Challenges in Cancer

Read time: 4 minutes I just returned from the Cancer Grand Challenges Summit, held March 5–8, 2024 in London, England. Cancer Grand Challenges was launched in 2020 as a collaboration between Cancer Research UK and the National Cancer Institute in the US, whereby they provide $25 million to international, multi-institutional teams working to address some of the most perplexing issues in the cancer field. I am LUNGevity’s representative on Team CANCAN, which is working to understand and treat cancer cachexia, the extreme loss of muscle and fat tissue (often called “wasting”) that often occurs in

Leveraging Genetics to Understand Why Younger Adults Are Developing Lung Cancer

Read Time: 5 minutes It’s a mystery that has been baffling researchers: Why do some people develop lung cancer in their 20s or 30s? While we used to think lung cancer was only caused by exposure to tobacco and environmental factors like radon, researchers are starting to learn that the development of lung cancer, particularly in younger adults, could have a hereditary component. LUNGevity partnered with the Lung Cancer Initiative, a leading nonprofit in North Carolina, to support research into this space by awarding one of our 2023 Career Development Awards to Jaclyn LoPiccolo, PhD, MD

From Leukemia to ALK+ NSCLC: Finding a New Way to Overcome Drug Resistance

Read Time: 5 minutes Approximately 4% of patients diagnosed with non-small cell lung cancer (NSCLC) will have their tumors test positive for an ALK biomarker. This means the ALK gene in the tumor cells has fused with another gene (most commonly EML4). This fusion produces a hyperactive ALK protein that causes cancer cells to grow and spread. Patients with ALK-positive lung cancer are often treated with a class of targeted therapies called TKIs (or tyrosine kinase inhibitors), which aim to target the effects of the hyperactive protein and stop tumor growth. However, ALK-positive lung cancer is